Treatment for Rheumatoid Arthritis Using Umbilical Cord Cells
Umbilical cord cells are useful in the treatment for rheumatoid arthritis. Researchers found that mesenchymal stem cells (MSCs) obtained from umbilical cord blood is helpful in suppressing inflammation and weakens the collagen-induced arthritis.
Rheumatoid arthritis can cause life crippling deformities in bones along with severe joint inflammation and pain. It was thus found that umbilical cord cells can be used to treat the symptoms and pain of rheumatoid arthritis.
Treatment for Rheumatoid Arthritis – Umbilical Cord Cells
A report published in the journal Arthritis Research and Therapy has revealed that the MSCs (mesenchymal stem cells) that are extracted from umbilical cord blood can alleviate joint inflammation and reduce the autoimmune response that leads to arthritis. This research was headed by Dr. Zhang Guo Li at the Peking University People’s Hospital in China.
- According to Dr. Li, the use of umbilical cord cells for treating rheumatoid arthritis is the first of its kind and has never been tried before. This is because not much was known of MSCs.
- These particular stem cells taken from the umbilical cord blood can suppress immune reposes profoundly. This is the very reason for their usage in treating autoimmune responses (rheumatoid arthritis is an autoimmune disorder).
- Also, right now, the only source of MSCs is the bone marrow. But, extracting these stem cells from the bone marrow can be a complicated process and also with age the potential of MSCs in the bone marrow is bound to decrease.
- On the other hand, the umbilical cord MSCs are much easier to collect.
The Research Study
The research was conducted on both human arthritis cells and even in mice that were suffering from arthritis.
- The immune cells of people who were suffering from rheumatoid arthritis were collected and were allowed to react with the stem cells from the umbilical cord.
- The MSCs were able to restrict the reproduction of the immune cells, reduce inflammatory processes and also suppress the invasive behavior of the immune cells.
- When mice that were suffering from arthritis were injected with the stem cells, the severity of the autoimmune response was also drastically reduced.
These umbilical cord cells (the MSCs) are a new pathway to an effective treatment for rheumatoid arthritis.