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Pancreatic Cancer Causes

Pancreatic cancer begins in pancreas tissues. Pancreas lies in the abdomen just behind the lower part of the stomach. These secrete enzymes which help in digestion and hormones which help in regulating sugar metabolism.

Often, pancreatic cancer has a poor prognosis even it is diagnosed early. Typically, it spreads rapidly. It is rarely detected in the initial stage. This is the major reason for many pancreatic cancer deaths. Symptoms do not develop till the cancer reaches advanced stage and it is not possible to remove it surgically.

Pancreatic Cancer Causes:
There are no exact causes of pancreatic cancer.

Understanding Pancreas:
Pancreas is 15 centimeters or 6 inches long and looks like a pear. This is an important organ of the digestive system. This secretes hormones like insulin for helping the body in sugar processing. Also, it produces digestive juices for digesting the food.

Formation of Pancreatic Cancer:
If the cells in the pancreas develop genetic mutations, it leads to pancreatic cancer. These cause cells to grow rapidly and even live after the death of normal cells, resulting in tumor formation.

Risk Factors of Pancreatic Cancer:
Following are the factors which increase the risk of pancreatic cancer:

  • Being black
  • Increasing age, particularly over 60 years
  • Smoking
  • Being obese or overweight
  • Chronic inflammation of pancreas
  • Family or personal history of pancreatic cancer
  • Diabetes
  • Family history of genetic syndromes which increase the risk of pancreatic cancer, such as Familial Atypical Mole-Malignant Melanoma, Lynch syndrome, Peutz-Jeghers syndrome and BRCA2 gene mutation
  • Ulcers

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