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Oral Lung Cancer Drug To Protect The Healthy Tissue From Radiation Effects!

A recent clinical testing of a substance named manganese superoxide dismutase (MnSOD) plasmid liposome in patients suffering from advanced stage non-small cell lung cancer has showed that it protects the healthy cells surrounding the tumor from the ill-effects of radiation and chemotherapy.

In this study, 10 patients who were suffering from non-small cell lung cancer which was in stage III (cannot be removed surgically) were given the above mentioned substance orally twice a week for a period of 7 weeks when they were undergoing radiation and chemotherapy.

MnSOD plasmid liposome is absorbed by the cells of the esophagus, a common area affected during chemotherapy and radiation treatment for lung cancer. It increases the antioxidant levels in the body.

Through this study, it was observed that higher levels of this substance can decrease the cell death and lower the numbers of inflammatory molecules apart from protecting the healthy esophageal cells from radiation effects.

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