Fat Stem Cells Worked Wonders For Patients Suffering From Peripheral Vascular Disease!
Three patients who have undergone a surgical procedure involving their own stem cells for peripheral vascular disease report amazing improvement since the period when the surgery was performed in the months of March and April.
Peripheral vascular disease (PVD) or peripheral artery disease (PAD) is a condition characterized by the narrowing and hardening of the arteries that supply blood to legs and feet due to the accumulation of plaque (fatty material) in them. This in turn leads to reduced blood flow and in severe cases the leg may get infected and has to be amputated.
The current study involved the extraction of fat (vascular) stem cells from fat tissue of the patients harvested through liposuction. These stem cells were then coated on the inside of a standard man-made bypass graft and transplanted into the patients’ bodies.
The entire procedure was performed at point-of-care meaning the extraction and coating of stem cells, and transplantation was all done at a time when the patient was lying on the operation table.
A team of researchers led by Charles B. Ross from the University of Louiseville performed the procedure.
The automated technology of extraction of fat stem cells and using them as the inner coating of medical devices was developed by Stuart Williams, Scientific and executive director of the Cardiovascular Innovation Institute and a team member of this study.
According to Ross, this technology can be made available at all the hospitals which perform vascular bypass surgeries.
Ross also opines that their procedure increases the long-term survival of the prosthetic graft in a patient’s body, as the stem cell lining used in them closely resembles a vein graft.
All the 3 patients on whom the trial was tested expressed the restoration of ‘feeling’ in the leg in which the stem cell graft was transplanted.