How Bacteria Become Antibiotics-Resistant

Researchers from the Penn University have found how certain bacteria have managed to be as a antibiotics-resistant. The results of their research are published in the April 28th 2011 issue of the journal Science.

The researchers found that a non-human bacteria Staphylococcus sciuri evolved a new gene cfr. The protein produced by this gene made the pathogen become drug resistant.

The gene was easily crossed to a bacteria present in the humans. Staphylococcus aureus has also developed this gene. Generally a protein RlmN helps in the proper functioning of cells by rightly placing certain molecular tags on the nucleotides of cells.

Binding of these proteins with antibiotics disrupt a vital section of the bacteria cells known as ribosomes, killing them eventually.

The researchers found that cfr protein also carry out tasks similar to RlmN of putting molecular tags. But, these proteins place the tags on different locations of the nucleotides.

As a result, RlmN cannot get attached to the antibiotics. The ribosomes function without any interruption and this how the bacteria evolve as drug-resistant.

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