Common Painkillers Can Blunt Antidepressants

Researchers at The Rockefeller University based in New York City have found that common painkillers like naproxen, aspirin and ibuprofen can reduce the impact of antidepressants known as selective serotonin reuptake inhibitors (SSRIs).

Popular antidepressants include Zoloft, Paxil, Prozac and Lexapro. Painkillers may interact with the antidepressants reducing the latter’s effectiveness.The researchers found that patients who had used painkillers reported much poorer results after using antidepressants.

However, the reason why painkillers blunt the effectiveness of antidepressants is not yet known. The researchers have formulated some hypotheses, which they will explore in future studies. Their findings were recently published online in the Proceedings of the National Academy of Sciences.

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