Potential Biliery Cancer Drug for Latter Stages is Discovered
The prognosis of cancer in the bile duct is very poor. Nearly 100,000 people are diagnosed with this disease every year throughout the world. Researchers from the Ohio University have discovered that the drug Selumetinib has the potential to treat the cancer even in the later stages. The results of the study are published in the April 2011 online edition of the Journal of Clinical Oncology.
The study has found that the drug works by inhibiting the protein MEK. The latter plays a vital role in the proliferation and survival of the malignant cells. The researchers believe that as part of further studies, this drug can be added to other drugs and make more potent in addressing bile duct cancer treatment.
An interesting observation the experts found that the drug was not effective in treating the disease in those patients who lacked the protein pERK in their bile duct cells.