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Nitrates Can Improve Bone Strength in Postmenopausal Women

According to a study published in JAMA, the usage of nitroglycerin ointment by postmenopausal women for about 2 years might increase bone mineral density and decrease bone loss. There is an increase in the number of cases of osteoporotic fractures throughout the world. Under such circumstances, Nitroglycerin seems to be a good option. It is inexpensive and easily available. The study was conducted by the researchers from Women’s College Research Institute and University of Toronto, Canada.

The researchers tested the role of nitroglycerin ointment in increasing the bone mineral density (BMD) at lumber spine, neck, hip and femoral (leg bone which extends from hip to knee). The study was conducted on 243 postmenopausal women between November 20065 and March 2010. Some of these participants used nitroglycerin ointment and the others placebo applied at night to upper arm for about 2 years. It was observed that women using nitroglycerin ointment had 6.7 % increased BMD at lumber spine, 6.2% at the hip and 7% at the femoral, as compared to the placebo. These women also had increased bone strength. Women using nitroglycerin ointment noticed increased bone formation and decreased bone loss.

According to the authors, daily use of nitroglycerin ointment can greatly improve the BMD, the bone structure and the bone strength. It can reduce the chances of non-vertebral and vertebral fractures.

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