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Uterus Health Decides the Gestational Period and Normal Birth Weight of Infant in IVF

Recent study published in an international journal for obstetricians “Fertility and Sterility”, shows that the uterus health is of greater relevance than the quality of the egg for a healthy newborn in assisted reproductive technologies for pregnancy like in-vitro fertilization.

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Dr. William Gibbons, director of The Family Fertility Program at Texas Children’s Hospital and his colleagues reviewed three years data which compared the average birth weight and the gestational period for the single births from the standard IVF, IVF with a surrogate and IVF with donor eggs. The ability to conceive mainly depends upon the quality of the egg, however, the gestational period and the birth weight depends significantly on the uterine environment which is affected in infertile women.

The researchers observed 300,000 IVF cycles which produced above 70,000 singleton pregnancies.The women who were diagnosed with uterine problems like fibroids had shorter gestational period and babies with lowest birth weight. This is the first time that a study demonstrates the uterus health as a key determinant for normal birth weight and length of the gestation.

According to Gibbons, in a standard IVF, the embryo is implanted in a woman who has recently undergone a controlled ovarian hyperstimulation, in donor egg IVF and surrogate IVF, the egg is implanted in an unstimulated and natural uterus. The researchers also studied the IVF where the patient’s own frozen egg is transferred into her own natural unstimulated uterus. It was observed that the babies with the frozen egg IVF had greater birth weight than those who were born out of standard IVF. The findings might help many women seeking pregnancy and the physicians to take the frozen embryo option into consideration.

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