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Why Diabetics Have Damaged Blood Vessels?

Febrauary 2, 2011: Researchers from the University of Washington have found out how diabetes patients have damaged blood vessels. The results of the study are published in the Journal of Biological Chemistry.

The experts identified two enzymes fatty acid synthase (FAS) and nitric oxide synthase (NOS) which are associated with the walls of the blood vessels. The former enzyme produces a lipid which allows the latter to hold the walls of the blood vessels together.

In a study carried out on experimental mice lacking the former enzyme, it was found that the lipid with binded the latter enzyme to the blood vessels was absent. It is a known fact that diabetic people have deficient FAS enzymes in their body owing to less insulin production or because of its resistance.

Researchers believe that discovery of drugs which can promote the levels of FAS enzyme can be quite beneficial to diabetic people in lowering the complications like heart attack, amputations, stroke and vision loss.

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