Does ‘Un-Growth Hormone’ Increase Longevity – Find Out What Researchers Say?
Un-growth hormone increases longevity – is it true? Do you know how the un-grown hormone increases longevity? Find out what the researchers have say about the un-growth hormone? Read on to know about the ‘Un-growth hormone’ increases longevity.
Some older adults’ intake growth hormone thinking that it will help t to revitalize them. But, the research may be counter-intuitive to this. A compound that acts in an opposite way as the growth hormone can reverse those some of the signs of aging that has been shown by a research team which includes a Saint Louis University Physician.
Their research was online published in the edition of the Proceedings of the National Academy of Sciences on December 6.
The findings are very significant, according to John E. Morley, M.D., director and study co-investigator of the divisions of geriatric medicine and endocrinology at Saint Louis University School of Medicine, as people sometimes take artificial growth hormone, believing that it will be the fountain of youth.
Morley says, “Many older adults have been taking the growth hormones in order to rejuvenate themselves”. These results strongly suggest that the growth hormone may be hazardous when given to older and middle aged people.
The scientists have studied the compound called MZ-5-156, a GHRH (growth hormone-releasing hormone) antagonist. They have conducted the research in a SAMP8 mouse model; it’s a strain which is engineered for the studies of the aging process. Overall, the researchers have that the GHRH antagonist compound – MZ-5-156 had all the positive effects on improving cognition, oxidative stress inside the brain, telomerase activity (these actions of the enzyme that protects the DNA material) and the life span, by decreasing the tumor activity.
Many GHRH antagonists like MZ-5-256, inhibited several cancers in humans, including breast, brain, lung and prostate cancers. It is also linked to the improvements in the short-term memory and had positive effects even on learning. The antioxidant actions have led to less oxidative stress by reversing cognitive impairment in the aging mouse.
The results have lead the team in order “to determine that the antagonists of the GHRH (growth hormone-releasing hormone) has the beneficial effect on the process of aging” says William A. Banks, M.D., lead study author and professor of internal medicine and geriatrics at the University of Washington School of Medicine in Seattle.
The study team included as its corresponding author Andrew V. Schally, M.D., Ph.D., a professor in the department of pathology and division of hematology/oncology at the University of Miami Miller School of Medicine.