What is Budd-Chairi Syndrome?

When clotting takes place in the vessels which carry de-oxygenated blood from liver to the heart, a condition called Budd-chairi syndrome occurs. This is the cause in 75 percent diagnosed cases. Narrowing of the blood vessel carrying blood from liver to the heart by a tumor in found in 25 percent cases.

Other minor possibilities are tuberculosis infection, use of contraceptives and pregnancy. 1 in every million persons gets this ailment and most of them are females.

Budd-Chairi Syndrome Symptoms:

  • Vomiting
  • Abdominal pain
  • Nausea
  • Smooth liver
  • Swollen liver
  • Jaundice
  • Swollen spleen
  • Hemoglobin in the urine
  • Increased weight
  • Leg swelling
  • Hypertension
  • Obstruction caused by clotting of blood in major liver vessels
  • Formation of a tumor in the liver vessels
  • Confusion
  • Changed levels of consciousness
  • Liver cirrhosis – Scarring of the fibrous tissues of the liver
  • Abnormal fa degeneration from the liver
  • Liver ascites – Leakage of fluids from the liver and intestines and their filling of the abdominal cavity
  • Centrilobular liver atrophy – Decrease in the size of the liver and complete wasting of the organ
  • Hemorrhage from esophageal varices – abnormal flow of blood from the esophagus to the liver owing to scaring of the tissues of this organ

Measurements of liver enzyme levels, ultrasound, MRI, CT scans and biopsy of liver are some of the ways by which the above mentioned signs of this condition can be diagnosed.

Treatment of Budd-Chairi Syndrome:
Outlook of the treatment depends on the exact cause of the condition. However, two-thirds of the patients are found to survive more than 10 years. If the symptoms are mild and diagnosed early, shunts can be used to divert the flow of blood around the site of clotting.

Liver transplantation is considered the effective treatment option. But unfortunately, it is the last resort, has complications to deal with and in 10 percent cases, the condition is found to make a comeback even after the transplantation.

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