Adie Syndrome Symptoms and Treatment

According to the National Institute of Neurological Disorders and Stroke (NINDS), Adie syndrome is believed to be caused by viral or bacterial infection in the portion of the brain which controls eye movements. Brain cells or neurons in this region get damaged.

The pupil of the eye and the system controlling the functions like digestion, respiration and heart rate, urination, sexual arousal and production of sweat and saliva are affected by this disorder. The disorder is mostly found to affect women with the average of onset being 32 years. It affects one eye generally but, there is a possibility of the disorder spreading to the other eye as well.

Symptoms of Adie Syndrome:

  • Abnormally dilated pupil
  • Excessive sweating
  • Loss of deep tendon reflexes
  • Difficulty in reading
  • Hyperopia – Defective condition of the eye which does not allow focusing on objects
  • Paresis – Partial loss of movements
  • Photophobia – Excessive sensitivity to light

Clinical examination, administration of low dose of pilocarpine, CT scans and MRI scans are some of the diagnostic tools used to find this condition. It is not life-threatening or disabling completely. In very rare cases, the condition is found to be hereditary.

Treatment of Adie Syndrome:
Reading glasses are prescribed to correct the problem of vision. Pilocarpine drops should be taken three times on daily basis which restrict the dilating of the pupil. In order to stop the excessive sweating problem drug therapy is initially tried. If it fails, then a surgical technique known as Endoscopic thoracic sympathectomy is taken up. Here tissues from either the neck, chest or lower back are destroyed.

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