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Waldenstrom’s Macroglobulinemia Symptoms

Waldenstrom’s macroglobulinemia symptoms primarily include bleeding, headache and fatigue. The cancer targets the white blood cells of the immune system and is among one percent of all other cancer types of white blood cells. It is a rare and slowly progressing cancer with nearly 1500 cases reported every year in the United States. The average age-group to be affected by this condition are 60-65 years or adolescents in their late teens.

Awareness of such rare form of cancer is imperative as early diagnosis increases the changes of getting healed. Very rarely the tumor metastasises or spreads to fresh locations. This article lists certain signs of this dreadful ailment.

Waldenstrom’s Macroglobulinemia Symptoms:

  • Fever
  • Bleeding
  • Weight loss
  • Weakness
  • Easy bruising
  • Pallor – Pale color of skin caused by stress or illness
  • Fatigue
  • Headache
  • Neurological symptoms
  • Frequent infections
  • Lassitude – Lack of energy
  • Dizziness
  • Vision problems
  • Enlarged liver
  • Low blood platelet level
  • Nosebleed
  • Chronic oozing of blood from gums
  • Stroke
  • Coma, though rare
  • Enlarged spleen
  • Anemia – Decrease in the number of red blood cells which provide oxygen to the body observed in 80 percent of patients
  • Reduced count of white blood cell – They provide protection to the body from external and internal threats
  • Splenomegaly – Enlargement of spleen
  • Lymphadenopathy – Swelling of the lymph nodes seen in 30-40 percent cases
  • High blood IgM level – Igm is first antibody to appear and protect our body when it gets exposed to disease causing organisms
  • Hepatomegaly – Enlarged liver
  • Rouleau formation – A condition where abnormal red blood cells stick together and form lump
  • Microlymphadenopathy
  • Abnormal proteins in blood
  • Purpura of fundus oculi
  • Peripheral neuropathy – Problem caused in the nerves that carry information to and from the brain. It is observed in 10 percent patients
  • Bence Jones proteinuria is a condition involving excretion of certain types of proteins through urine. It is found in 40 percent patient.
  • Hypercalcemia – Increased levels of calcium in the blood found in 4 percent patients during the diagnosis of the Waldenstrom’s Macroglobulinemia symptoms

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