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Symptoms of Sezary Syndrome

Symptoms of sezary syndrome mostly affect men belonging to the age group of 55-60 years. The average survival rate of this very rare form of cancer is 5 years. 0.3 percent cases of this ailment per 100,000 people are reported every year in the western countries. It comes under a group of skin cancer type known as Mycosis fungoides.

Nearly 1000 new cases of mycosis fungoides are known every year in the United States. As cause of the disease is unknown, awareness about the signs to look out for become imperative. This article tries to gain further insight on the signs of this rare cancer.

Symptoms of Sezary Syndrome:

  • Itching
  • Redness of skin
  • Alopecia
  • Dystrophic nail
  • Patches
  • Plaques
  • Tumors on the skin
  • Swelling of the Lymph nodes

Diagnosis of Symptoms of Sezary Syndrome:

  • Physical Exam: History of the patient with details of past illnesses is collected. Signs of any lumps or lesions are checked.
  • Complete Blood Count: The count of red blood cells, white blood cells, platelets and the levels of hemoglobin can be known from the collected blood sample.
  • Biopsy: Here a portion of the affected skin is separated from the body and signs of cancer are looked for under very powerful microscopes. However, to diagnose Mycosis fungoides cancer skin samples from more than one area should be collected.
  • Immunophonotyping: It is a special diagnostic technique used to detect signs of specific types of cancer. Special staining of the blood cells are used to find the chemicals or organisms whose presence in the blood confirm the condition.
  • Immunogenotyping: Genes are the chemical instructions followed by cells to perform their functions. These genes are made up of DNA and RNA molecules arranged in certain patterns. But in patients suffering from sezary syndrome, the DNA is arranged in single pattern. In Immunogenotyping, a sample of the DNA of the cancerous skin cells is studied after conducting biopsy.

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