Non-Hodgkin’s Lymphoma Symptoms

Non-Hodgkin’s lymphoma symptoms vary largely depending on their severity from being aggressive to slowly progressive ones. According to the National Cancer Institute, 65,540 new cases and 20,210 deaths are estimated to be reported of this cancer in 2010 in the United States.

Non Hodgkin Lymphoma Symptoms:

Multiple Swelling of Lymph Nodes: The natural protection system of our body is called the immune system. A very important organ of this system is the small, circular ball shaped lymph node. It is present through out the body. It acts as a filter to trap foreign bodies. It also stores cells of the immune system like B cells and T cells which kill the foreign threats.

When the body gets affected by any condition, this organ swells. It has a very special significance in dealing with cancer. Stage of this ailment affecting an organ is decided by its condition and the treatment is planned accordingly. Non-hodgkin’s disease is a cancer which develops in this very organ.

Though symptoms remain latent in the initial stages, they become apparent with the progression of the disease. Painless swelling develops in locations like the neck, groin and the underarm. Other signs are:

  • Enlarged liver
  • Enlarged spleen
  • Night sweats
  • Unexplained fever
  • Itchy skin
  • Flu-like symptoms
  • Unexplained weight loss
  • Tiredness
  • Itchy skin
  • Red skin patches
  • Shortness of breath
  • Anemia
  • Fatigue
  • Pallor

Types of Non-Hodgkin’s Lymphoma:

The signs of Non-hodgkin’s disease based on its severity are classified by the Working Formulation guideline. It was first published in 1982 and was last published in 2001 by the World Health Organisation (WHO). According to it, they are four grades of this cancer, namely; the low, intermediate, high and miscellaneous.

Low Grade Malignant Lymphoma:

  • Follicular and mixed type involving small cleaved and large cell
  • Follicular involving only small cleaved cells
  • Chronic lymphocytic leukemia

Intermediate Grade Malignant Lymphoma:

  • Diffuse and large cell
  • Diffuse, mixed small and large cell
  • Diffuse and Ai??small cleaved cell
  • Follicular mainly involving large cell

High Grade Malignant Lymphoma:

  • Burkitt’s lymphoma
  • Lymphoblastic cancer
  • Immunoblastic cancer


  • Histiocytic
  • Composite
  • Extramedullary plasmacytoma
  • Mycosis fungoides

hodgkin’s lymphoma symptoms are asymptomatic (without any sign) and mimic signs of other ailments in the initial stages. Blood test, X-rays, CT scanning, MRI’s, PET scans and bone marrow biopsy are the diagnostic techniques used to find the signs eventually.

1 response to Non-Hodgkin’s Lymphoma Symptoms

  1. The symptoms for this deadly disease are so common, it’s terrifying! How are you suppose to know if you have a really bad cold or cancer?
    My sister was recently diagnosed with NHL and the only reason we discovered it was that she was too tired to make it to soccer for several weeks in a row. We never expected NHL, but that’s what it turned out to be.
    Thanks for this useful info,

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